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Fmoc-Val-Ala-PAB(m-PEG8) Size:100mg a novel and potent GSPT1

SKU: 80610052875

4.4
USD195.00 USD228.00

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Description

a novel and potent GSPT1 degrader displaying selectivity over 9000 proteins

352 SMILES OCCCC#CC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

166 Purity (HPLC) >= 95% Solubility DMSO

Product Name Biotin-PEG4-acid Synonyms CAS Number 721431-18-1 Related CAS Molecular Formula C21H37N3O8S Molecular Weight 491

Fmoc-Val-Ala-PAB(m-PEG8) Size:100mg a novel and potent GSPT1SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine (PSAR), to enhance aqueous solubility. Solubility and physicochemical properties can be finely tuned

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