Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG8)-PNP mal-hexanoyl Product Name Azide-Dap(m-PEG4)-Val-Ala-PAB(m-PEG4)-Exatecan Synonyms CAS

Product Name Azide-Dap(m-PEG4)-Val-Ala-PAB(m-PEG4)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C63H84FN11O19 Molecular Weight 1318

Product Name DOTA-tris(t-Bu)ester-C3-alcohol Synonyms CAS Number n/a Related CAS Molecular Formula C31H59N5O8 Molecular Weight 629

diAcFAM is typically supplied as a cell-permeable ligand that

Datasheet          MSDS

Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG8)-PNP mal-hexanoyl Product Name Azide-Dap(m-PEG4)-Val-Ala-PAB(m-PEG4)-Exatecan Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating