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Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG8)-PNP Size:100mg 109 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCOCCOCCOCCNC(=O)CCN2C(=O)C=CC2=O)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC)

SKU: 70410055243

4.3
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Description

109 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCOCCOCCOCCNC(=O)CCN2C(=O)C=CC2=O)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

such as sodium 2-mercaptoethanesulfonate (MESNA)

no side reactions occur – the label and detection tags react selectively and specifically with one another

Product Name DOTA-tris(t-Bu)ester-C6-amine Synonyms CAS Number n/a Related CAS Molecular Formula C34H66N6O7 Molecular Weight 670

Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG8)-PNP Size:100mg 109 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCOCCOCCOCCNC(=O)CCN2C(=O)C=CC2=O)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating

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